inflammatory angiogenesis involves ZC3H12A encoding gene induction of monocyte chemoattractant protein-1 Novel (MCP-1) induced protein-1 (MCPIP1) having deubiquitinase and antidicer RNase activity. Whether and how the enzymatic activity MCPIP1 MCPIP1 mediate biological function is unknown.

The study comes with human umbilical vein endothelial cells showed that MCPIP-induced angiogenesis mediated by hypoxia inducible factor (HIF-1α), vascular endothelial growth factor (VEGF), and silent information regulator (SIRT-1) induction resulted in inhibition of angiogenesis inhibitor thrombospondin- 1. MCPIP1 expression inhibits the production of antiangiogenic microRNA (mir) -20b and -34a which suppresses translation of HIF-1α and SIRT-1, respectively.

The MCPIP D141N mutant RNase-dead not only did not induce angiogenesis but also failed to inhibit the production of miR-20b and -34a shows that the RNase activity antidicer of MCPIP1 involved in angiogenesis-mediated MCPIP. Mimetics of miR-20b and -34a MCPIP1-induced angiogenesis inhibiting confirm that MCPIP1 pressing the biogenesis of miR-20b and -34a. Furthermore, our results indicate that MCPIP expression induces nuclear translocation of HIF-1α.

We show that under hypoxia angiogenesis mediated through induction MCPIP1 and under normoxia, in vitro, MCPIP deubiquitinates ubiquitinated HIF-1α, and stabilized HIF-1α into the nucleus to promote transcription of target genes, cyclooxygenase-2 and VEGF, suggesting that the activity deubiquitinase of MCPIP also can promote angiogenesis. These results show for the first time that the RNase activity antidicer of MCPIP1 very important in mediating the biological function MCPIP, ie angiogenesis.

Antidicer RNAse activity of <em>monocyte</em> <em>chemotactic</em> <em>protein</em>-induced <em>protein</em>-<em>1</em> is critical for inducing angiogenesis.
Antidicer RNAse activity of monocyte chemotactic protein-induced protein1 is critical for inducing angiogenesis.

[Effect monocytes chemotactic protein -3 ICAM- one , VCAM- one , TF and TFPI expression and apoptosis in human umbilical vein endothelial cells].

OBJECTIVE
To determine the effect of monocyte chemotactic protein-3 (MCP-3) on the expression of adhesion between the molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), tissue factor (TF, and tissue factor pathway inhibitor (TFPI ) and apoptosis in human umbilical vein endothelial cells (HUVECs).


METHOD
Cultured HUVECs treated with MCP-3 at a predetermined optimum concentration 1 hour after treatment with or without MCP-3 antibody (20 ng / ml), PI3K inhibitors, or LY-294 002 (5 mmol / ml). The expression of ICAM-1, VCAM-1, TF and TFPI was analyzed using RT-PCR and Western blot after treatment. MCP-3 mRNA and protein expression was detected in HUVECs exposed to 50 ug / ml ox-LDL for 24 hours. The cell apoptosis and caspase-3 protein production in HUVECs treated with MCP-3 or MCP-3 plus CCR2 antagonist for 24 hours and 48 hours was evaluated by flow cytometry and Western blotting.


RESULTS
At the optimal concentration of 0.3 ng / ml, MCP-3 treatment for 24 hours due to significantly increased ICAM-1, VCAM-1, and the expression of TF by lowering expression of TFPI in HUVECs (P <0.05), and the effects such as by the application significantly inhibited MCP-3 antibody, PI3K inhibitor, or LY-294 002 (P <0.05). Ox-LDL exposure significantly increased the expression of MCP-3 in HUVECs (P <0.05). HUVECs showed significantly increased the level of apoptosis after treatment with MCP-3 or MCP-3 plus CCR2 antagonist (P <0.05), and the rate of apoptosis increased significantly as a long-term treatment (P <0.05); caspase-3 protein expression in the cell showed the same pattern of changes following the treatment.

Monocyte Chemotactic Protein-4 (CCL13) Protein
20-abx263240
  • EUR 230.00
  • EUR 1609.00
  • EUR 328.00
  • 1 µg
  • 50 ug
  • 5 ug
  • Shipped within 5-10 working days.
Active Monocyte Chemotactic Protein 4 (MCP4)
4-APA216Hu51
  • EUR 718.24
  • EUR 295.00
  • EUR 2418.40
  • EUR 872.80
  • EUR 1645.60
  • EUR 544.00
  • EUR 5896.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q99616
  • Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 10.7kDa
  • Isoelectric Point: 10
Description: Recombinant Human Monocyte Chemotactic Protein 4 expressed in: Yeast
Monocyte Chemotactic Protein 4 (MCP4) Antibody
20-abx177586
  • EUR 398.00
  • EUR 133.00
  • EUR 1094.00
  • EUR 537.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Monocyte Chemotactic Protein 4 (MCP4) Antibody
20-abx177588
  • EUR 1233.00
  • EUR 592.00
  • 1 mg
  • 200 ug
  • Please enquire.
Monocyte Chemotactic Protein 4 (MCP4) Antibody
20-abx177589
  • EUR 1316.00
  • EUR 634.00
  • 1 mg
  • 200 ug
  • Please enquire.
Monocyte Chemotactic Protein 4 (MCP4) Antibody
20-abx104987
  • EUR 398.00
  • EUR 133.00
  • EUR 1107.00
  • EUR 537.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Monocyte Chemotactic Protein 4 (MCP4) Antibody
20-abx173604
  • EUR 787.00
  • EUR 411.00
  • 1 mg
  • 200 ug
  • Please enquire.
Eukaryotic Monocyte Chemotactic Protein 4 (MCP4)
4-EPA216Hu51
  • EUR 539.04
  • EUR 247.00
  • EUR 1746.40
  • EUR 648.80
  • EUR 1197.60
  • EUR 424.00
  • EUR 4216.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q99616
  • Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 10.7kDa
  • Isoelectric Point: 10
Description: Recombinant Human Monocyte Chemotactic Protein 4 expressed in: Yeast
Recombinant Monocyte Chemotactic Protein 4 (MCP4)
4-RPA216Hu01
  • EUR 530.08
  • EUR 245.00
  • EUR 1712.80
  • EUR 637.60
  • EUR 1175.20
  • EUR 418.00
  • EUR 4132.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q99616
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 41.0kDa
  • Isoelectric Point: 8.8
Description: Recombinant Human Monocyte Chemotactic Protein 4 expressed in: E.coli
Human Monocyte Chemotactic Protein 4 (MCP4) Protein
20-abx167892
  • EUR 732.00
  • EUR 286.00
  • EUR 2305.00
  • EUR 885.00
  • EUR 523.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Dog Monocyte Chemotactic Protein 4 (MCP4) Protein
20-abx654389
  • EUR 648.00
  • EUR 272.00
  • EUR 1998.00
  • EUR 773.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.
Horse Monocyte Chemotactic Protein 4 (MCP4) Protein
20-abx654390
  • EUR 648.00
  • EUR 272.00
  • EUR 1998.00
  • EUR 773.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.
Human Monocyte Chemotactic Protein 4 (MCP4) Protein
20-abx651547
  • EUR 746.00
  • EUR 300.00
  • EUR 2346.00
  • EUR 899.00
  • EUR 537.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Recombinant Human Monocyte Chemotactic Protein-4 (CCL13)
7-01975 2µg Ask for price
Recombinant Human Monocyte Chemotactic Protein-4 (CCL13)
7-01976 10µg Ask for price
Recombinant Human Monocyte Chemotactic Protein-4 (CCL13)
7-01977 1mg Ask for price
Rat Monocyte Chemotactic Protein 4 ELISA kit
E02M0253-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Rat Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rat Monocyte Chemotactic Protein 4 ELISA kit
E02M0253-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Rat Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rat Monocyte Chemotactic Protein 4 ELISA kit
E02M0253-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Rat Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human Monocyte Chemotactic Protein 4 ELISA kit
E01M0253-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Human Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human Monocyte Chemotactic Protein 4 ELISA kit
E01M0253-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Human Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human Monocyte Chemotactic Protein 4 ELISA kit
E01M0253-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Human Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rabbit Monocyte Chemotactic Protein 4 ELISA kit
E04M0253-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Rabbit Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rabbit Monocyte Chemotactic Protein 4 ELISA kit
E04M0253-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Rabbit Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rabbit Monocyte Chemotactic Protein 4 ELISA kit
E04M0253-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Rabbit Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Monocyte Chemotactic Protein 4 ELISA kit
E03M0253-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Mouse Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Monocyte Chemotactic Protein 4 ELISA kit
E03M0253-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Mouse Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Monocyte Chemotactic Protein 4 ELISA kit
E03M0253-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Mouse Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Monocyte Chemotactic Protein 4 (MCP4) Antibody (APC)
20-abx177587
  • EUR 1094.00
  • EUR 537.00
  • 1 mg
  • 200 ug
  • Please enquire.
Human Monocyte Chemotactic Protein 4 ELISA Kit
ELA-E0216h 96 Tests
EUR 824
Goat Monocyte Chemotactic Protein 4 ELISA kit
E06M0253-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Goat Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat Monocyte Chemotactic Protein 4 ELISA kit
E06M0253-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Goat Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat Monocyte Chemotactic Protein 4 ELISA kit
E06M0253-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Goat Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Dog Monocyte Chemotactic Protein 4 ELISA kit
E08M0253-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Canine Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Dog Monocyte Chemotactic Protein 4 ELISA kit
E08M0253-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Canine Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Dog Monocyte Chemotactic Protein 4 ELISA kit
E08M0253-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Canine Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Pig Monocyte Chemotactic Protein 4 ELISA kit
E07M0253-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Porcine Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Pig Monocyte Chemotactic Protein 4 ELISA kit
E07M0253-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Porcine Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Pig Monocyte Chemotactic Protein 4 ELISA kit
E07M0253-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Porcine Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Monkey Monocyte Chemotactic Protein 4 ELISA kit
E09M0253-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Monkey Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Monkey Monocyte Chemotactic Protein 4 ELISA kit
E09M0253-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Monkey Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Monkey Monocyte Chemotactic Protein 4 ELISA kit
E09M0253-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Monkey Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human monocyte chemotactic protein 4,MCP-4 ELISA kit
201-12-0069 96 tests
EUR 440
  • This monocyte chemotactic protein 4 ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.
Rat Monocyte Chemotactic Protein 4 (MCP-4) CLIA Kit
abx197298-96tests 96 tests
EUR 825
  • Shipped within 5-12 working days.
Rat monocyte chemotactic protein 4,MCP-4 ELISA kit
CN-01421R1 96T
EUR 464
Rat monocyte chemotactic protein 4,MCP-4 ELISA kit
CN-01421R2 48T
EUR 313
Mouse monocyte chemotactic protein 4,MCP-4 ELISA kit
CN-02290M1 96T
EUR 481
Mouse monocyte chemotactic protein 4,MCP-4 ELISA kit
CN-02290M2 48T
EUR 332
Human monocyte chemotactic protein 4,MCP-4 ELISA kit
CN-03427H1 96T
EUR 458
Human monocyte chemotactic protein 4,MCP-4 ELISA kit
CN-03427H2 48T
EUR 307
Human monocyte chemotactic protein 4, MCP-4 ELISA kit
CSB-E09762h-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Human monocyte chemotactic protein 4, MCP-4 in samples from serum, plasma, cell culture supernates, urine. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Human monocyte chemotactic protein 4, MCP-4 ELISA kit
1-CSB-E09762h
  • EUR 500.00
  • EUR 3402.00
  • EUR 1820.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Human monocyte chemotactic protein 4, MCP-4 in samples from serum, plasma, cell culture supernates, urine. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Rat monocyte chemotactic protein 4(MCP-4)ELISA Kit
GA-E0204RT-48T 48T
EUR 317
Rat monocyte chemotactic protein 4(MCP-4)ELISA Kit
GA-E0204RT-96T 96T
EUR 496
Canine monocyte chemotactic protein 4(MCP-4)ELISA Kit
GA-E0078CN-48T 48T
EUR 402
Canine monocyte chemotactic protein 4(MCP-4)ELISA Kit
GA-E0078CN-96T 96T
EUR 684
Human monocyte chemotactic protein 4(MCP-4)ELISA Kit
GA-E0108HM-48T 48T
EUR 289
Human monocyte chemotactic protein 4(MCP-4)ELISA Kit
GA-E0108HM-96T 96T
EUR 466
Human monocyte chemotactic protein 4(MCP-4)ELISA Kit
QY-E03923 96T
EUR 361
Rat monocyte chemotactic protein 4(MCP-4)ELISA Kit
QY-E11448 96T
EUR 361
Mouse monocyte chemotactic protein 4(MCP-4)ELISA Kit
QY-E21023 96T
EUR 361
Human Monocyte Chemotactic Protein 4 (MCP4) Protein (Active)
20-abx655775
  • EUR 1191.00
  • EUR 425.00
  • EUR 4017.00
  • EUR 1455.00
  • EUR 815.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.
Human Monocyte Chemotactic Protein 4 (MCP4) Protein (Active)
20-abx651417
  • EUR 982.00
  • EUR 342.00
  • EUR 3237.00
  • EUR 1191.00
  • EUR 676.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
MCP-4 Monocyte Chemotactic Protein-4 Human Recombinant Protein (CCL13)
PROTQ99616-1 Regular: 10ug
EUR 317
Description: Monocyte Chemotactic Protein-4 Human Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 75 amino acids and having a molecular mass of 8.6 kDa. The MCP-4 is purified by proprietary chromatographic techniques.
Canine Monocyte Chemotactic Protein 4 (MCP4) ELISA Kit
DLR-MCP4-c-48T 48T
EUR 556
  • Should the Canine Monocyte Chemotactic Protein 4 (MCP4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Canine Monocyte Chemotactic Protein 4 (MCP4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Canine Monocyte Chemotactic Protein 4 (MCP4) ELISA Kit
DLR-MCP4-c-96T 96T
EUR 728
  • Should the Canine Monocyte Chemotactic Protein 4 (MCP4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Canine Monocyte Chemotactic Protein 4 (MCP4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Human Monocyte Chemotactic Protein 4 (MCP4) ELISA Kit
DLR-MCP4-Hu-48T 48T
EUR 479
  • Should the Human Monocyte Chemotactic Protein 4 (MCP4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Monocyte Chemotactic Protein 4 (MCP4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Human Monocyte Chemotactic Protein 4 (MCP4) ELISA Kit
DLR-MCP4-Hu-96T 96T
EUR 621
  • Should the Human Monocyte Chemotactic Protein 4 (MCP4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Monocyte Chemotactic Protein 4 (MCP4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Guinea pig Monocyte Chemotactic Protein 4 ELISA kit
E05M0253-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Guinea pig Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Guinea pig Monocyte Chemotactic Protein 4 ELISA kit
E05M0253-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Guinea pig Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Guinea pig Monocyte Chemotactic Protein 4 ELISA kit
E05M0253-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Guinea pig Monocyte Chemotactic Protein 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Guinea Pig monocyte chemotactic protein 4 ELISA Kit
ELA-E0216Gu 96 Tests
EUR 928
Human CCL13(Monocyte Chemotactic Protein 4) ELISA Kit
EH0056 96T
EUR 524.1
  • Detection range: 15.625-1000 pg/ml
  • Uniprot ID: Q99616
  • Alias: CCL13(Monocyte Chemotactic Protein 4)/MCP-4/C-C motif chemokine 13/chemokine(C-C motif) ligand 13/CKb10/MCP4/MCP-4Monocyte chemoattractant protein 4/MGC17134/NCC-1Monocyte chemotactic prote
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Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml
Canine Monocyte Chemotactic Protein 4(MCP4)ELISA Kit
GA-E0026CN-48T 48T
EUR 402
Canine Monocyte Chemotactic Protein 4(MCP4)ELISA Kit
GA-E0026CN-96T 96T
EUR 684
Monocyte Chemotactic Protein 4 (MCP4) Polyclonal Antibody (Human)
4-PAA216Hu01
  • EUR 232.00
  • EUR 2285.00
  • EUR 574.00
  • EUR 289.00
  • EUR 208.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MCP4 (Gln24~Thr98)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human Monocyte Chemotactic Protein 4 (MCP4)
Horse Monocyte Chemotactic Protein 4(MCP4)ELISA Kit
QY-E120036 96T
EUR 492
for Monocyte Chemotactic Protein 4 (MCP4)ELISA kit
SEA216Hu-10x96wellstestplate 10x96-wells test plate
EUR 4273.35
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of for Monocyte Chemotactic Protein 4 (MCP4) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay:
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of for Monocyte Chemotactic Protein 4 (MCP4) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
for Monocyte Chemotactic Protein 4 (MCP4)ELISA kit
SEA216Hu-1x48wellstestplate 1x48-wells test plate
EUR 439.57
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of for Monocyte Chemotactic Protein 4 (MCP4) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay:
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of for Monocyte Chemotactic Protein 4 (MCP4) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
for Monocyte Chemotactic Protein 4 (MCP4)ELISA kit
SEA216Hu-1x96wellstestplate 1x96-wells test plate
EUR 585.1
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of for Monocyte Chemotactic Protein 4 (MCP4) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay:
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of for Monocyte Chemotactic Protein 4 (MCP4) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
for Monocyte Chemotactic Protein 4 (MCP4)ELISA kit
SEA216Hu-5x96wellstestplate 5x96-wells test plate
EUR 2332.95
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of for Monocyte Chemotactic Protein 4 (MCP4) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay:
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of for Monocyte Chemotactic Protein 4 (MCP4) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
ELISA Kit for Monocyte Chemotactic Protein 4 (MCP4)
4-SEA216Hu
  • EUR 4324.00
  • EUR 2283.00
  • EUR 586.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Monocyte Chemotactic Protein 4 elisa. Alternative names of the recognized antigen: CCL13
  • SCYA13
  • NCC1
  • SCYL1
  • CKb10
  • Chemokine C-C-Motif Ligand 13
  • Small Inducible Cytokine Subfamily A(Cys-Cys)Member 13
  • CK-beta-10
  • Monocyte chemoattra
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Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Monocyte Chemotactic Protein 4 (MCP4) in samples from Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.
Canine Monocyte Chemotactic Protein 4 (MCP4) ELISA Kit
RDR-MCP4-c-48Tests 48 Tests
EUR 591
Canine Monocyte Chemotactic Protein 4 (MCP4) ELISA Kit
RDR-MCP4-c-96Tests 96 Tests
EUR 823
Human Monocyte Chemotactic Protein 4 (MCP4) ELISA Kit
RDR-MCP4-Hu-48Tests 48 Tests
EUR 500
Human Monocyte Chemotactic Protein 4 (MCP4) ELISA Kit
RDR-MCP4-Hu-96Tests 96 Tests
EUR 692
Recombinant (E.Coli) Human Monocyte Chemotactic Protein-4 (CCL13)
RP-1023 10 ug
EUR 286
Human Monocyte Chemotactic Protein 4 (MCP4) ELISA Kit
RD-MCP4-Hu-48Tests 48 Tests
EUR 478
Human Monocyte Chemotactic Protein 4 (MCP4) ELISA Kit
RD-MCP4-Hu-96Tests 96 Tests
EUR 662
Human Monocyte Chemotactic Protein 4 (MCP-4/CCL13) CLIA Kit
abx197299-96tests 96 tests
EUR 825
  • Shipped within 5-12 working days.
Guinea Pig monocyte chemotactic protein 4,MCP-4 ELISA kit
CN-00243G1 96T
EUR 481
Guinea Pig monocyte chemotactic protein 4,MCP-4 ELISA kit
CN-00243G2 48T
EUR 332
Mouse monocyte chemotactic protein 4(MCP-4/CCL13)ELISA kit
GA-E0160MS-48T 48T
EUR 336
Mouse monocyte chemotactic protein 4(MCP-4/CCL13)ELISA kit
GA-E0160MS-96T 96T
EUR 534
ELISA kit for Human Monocyte chemotactic protein 4 (MCP-4)
KTE62593-48T 48T
EUR 267
  • Chemokine (C-C motif) ligand 13 (CCL13) is a small cytokine belonging to the CC chemokine family.The chemokines are secreted proteins involved in immunoregulatory and inflammatory processes. Naruse et al. (1996) identified on chromosome 17q11.2 a clu
  • Show more
Description: Quantitative sandwich ELISA for measuring Human Monocyte chemotactic protein 4 (MCP-4) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Human Monocyte chemotactic protein 4 (MCP-4)
KTE62593-5platesof96wells 5 plates of 96 wells
EUR 1705
  • Chemokine (C-C motif) ligand 13 (CCL13) is a small cytokine belonging to the CC chemokine family.The chemokines are secreted proteins involved in immunoregulatory and inflammatory processes. Naruse et al. (1996) identified on chromosome 17q11.2 a clu
  • Show more
Description: Quantitative sandwich ELISA for measuring Human Monocyte chemotactic protein 4 (MCP-4) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Human Monocyte chemotactic protein 4 (MCP-4)
KTE62593-96T 96T
EUR 441
  • Chemokine (C-C motif) ligand 13 (CCL13) is a small cytokine belonging to the CC chemokine family.The chemokines are secreted proteins involved in immunoregulatory and inflammatory processes. Naruse et al. (1996) identified on chromosome 17q11.2 a clu
  • Show more
Description: Quantitative sandwich ELISA for measuring Human Monocyte chemotactic protein 4 (MCP-4) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
Guinea Pig monocyte chemotactic protein 4(MCP-4)ELISA Kit
QY-E90048 96T
EUR 478
Monocyte Chemotactic Protein-1 (human)
H-5826.0100 0.1mg
EUR 708
Description: Sum Formula: C379H610N108O114S5; CAS# [126463-99-8] net


CONCLUSION
ox-LDL can cause MCP-3 expression in HUVECs. MCP-3 and induces apoptosis of HUVECs significantly affect cell function partly through the PI3K pathway signaling.